Generic Singulair Maximize

Generic Singulair Montelukast

Generic Singulair (montelukast) inhibits cysteinyl  of leukotriene receptor of  the respiratory tract epithelium (Leukotriene Receptor Antagonists

More details

  • 5mg - 30 tablets
  • 5mg - 90 tablets
  • 10mg - 30 tablets
  • 10mg - 90 tablets

398 Items in stock

On sale On sale!


Ask a question (0)

By buying this product you can collect up to 10 loyalty points. Your cart will total 10 points that can be converted into a voucher of $2.00.

  • More info
  • Reviews (0)
  • Questions (0)

The information provided below corresponds to the official product information from Patient Information Leaflet provided by the manufacturer. The text does not contain any of medical advices, mode of administration and prescription plans. Before beginning any treatment, we kindly advise you to consult your healthcare provider.

Generic Singulair. Cheap Singulair online. Montelukast by Cipla

Drugs name: Montelukast

Manufacturer: Cipla

International non-proprietary name : Montelukast

How does generic Singulair work?

Generic Singulair (montelukast) inhibits cysteinyl  of leukotriene receptor of  the respiratory tract epithelium (Leukotriene Receptor Antagonists (LTRAs) and thereby simultaneously possesses the ability to inhibit bronchoconstriction due to inhalation of cysteinyl-leukotriene LTD4 in patients with bronchial asthma. The dose of montelukast   5 mg is sufficient for relief of bronchoconstriction induced by LTD4. Generic Singulair causes bronchodilation within 2 hours after ingestion and may enhance bronchodilation caused by β2-agonists.

How generic Singulair is absorbed, metabolized and eliminated out of the organism?



Generic Singulair (Montelukas) is rapidly and almost completely absorbed after oral administration. Food intake does not affect the bioavailability and maximum plasma concentrations (Cmax) of generic Singulair. In patients which took generic  Sungulair 10mg  Cmax is achieved in 3 hours. Oral bioavailability is 64%. The bioavailability of generic  Singulair of different dosages is different.


More than 99% of Montelukast binds to plasma proteins. The volume of distribution of montelukast averages 8.11 liters.


Montelukast is actively metabolized in the liver. It is expected that the process of metabolism of montelukast involved isozymes of cytochrome P450 CYP (3A4 and 2C9). In therapeutic concentrations montelukast does  not inhibit cytochrome P450 isozymes CYP: 3A4, 2C9, 1A2, 2A6, 2C19 and 2D6.


The Clearance of montelukast in healthy adults is in average 45 ml/min. After oral  oral application of montelukast, 86% of the amount is excreted with the feces within 5 days and less than 0,2% with the urine. Montelukast and its metabolites are excreted almost exclusively via the bile.

Half-life period pf montelukast in young healthy adults ranges from 2,7 to 5,5 hours. The pharmacokinetics of montelukast remains almost linear at oral doses above 50 mg. In application of generic Singulair in the morning and evening hours pharmacokinetic differences were not observed.

Pharmacokinetics in different patient's groups


The pharmacokinetics of montelukast in women and men is similar.

Older patients

When generic Singulair 10mg is administered once daily pharmacokinetic indexes and bioavailability are similar in elderly and young patients.

Liver failure

In patients with hepatic insufficiency of mild to moderate severity and clinical manifestations of liver cirrhosis there were observed slowing of montelukast metabolism, an increase in areas under the pharmacokinetic curve "concentration-time» (AUC) by approximately 41% after a application of single dose 10 mg. The correction of montelukast dose for patients  with hepatic insufficiency of mild to moderate severity is not required. Generic Singulair is not recommended for patients with severe hepatic insufficiency.


There are no any significant differences in  pharmacokinetic effects in patients of different races.

Renal failure

Because generic Singulair (montelukast) is no excreted with the urine, the pharmacokinetics of montelukast in patients with renal insufficiency has not been evaluated. The correction of Montelukast dose for this category of patients is not required.

When generic Singulair is prescribed?

Generic Singulair is indicated in prophylaxis and prolonged treatment of bronchial asthma in adults and children beginning from 14 years of age including daily and night symptoms of the disease, treatment of aspirin-dependent patients with bronchial asthma and prevention of bronchospasm caused by physical overload.

Generic Singulair is used to a arrest daily and night symptoms of seasonal allergic rhinitis (in adults and children over 6 years of age) and all year round allergic rhinitis (in adults and children over 14 years of age).

When generic Singulair is contraindicated?

Generic Singulair should not be taken in children under 14 years of age and patients with known hypersensitivity to any of the drug ingredients. Singulair should be used with caution in patients with mild and moderate liver diseases. The use of Singulair in patients with severe liver diseases is not recommended.

Make sure to consult your health care provider if you are pregnant and breastfeeding. The treatment with Singulair should be carried only by a health care provider supervision.  

Generic Singulair special cautions:

SINGULAIR tablets are not recommended for the treatment of acute asthma attacks. The dose of  inhaled glucocorticosteroids used in conjunction with SINGULAIR can be gradually lowered under medical supervision. The treatment with corticosteroids should not be rapidly replaced on generic Singulair. In those patients who used a combined therapy of Singulair there were reported the following Generic Singulair side effects:  eosinophilia, vascular rash, worsening of pulmonary symptoms, cardiac complications and / or neuropathy.  Although the causal relationship of theses adverse effects with combined therapy of generic Singulair with glucocorticosteroids was not studied properly.  

How generic Singulair is taken?

Generic Singulair is indicated only by a health care provider. Do not take Singulair generic without medical approval. For the treatment of bronchial asthma in adults the recommended dose is one tablet once daily. The dose is prescribed individually. Patients suffering from bronchial asthma and allergic rhinitis should take one tablet of generic Singulair once daily.

Which generic Singulair side effects are possible

In general generic Singulair is well tolerated. Generic Singulair side effects are mild or moderate and do not require the cessation of therapy. During the clinical trials there were observed the following Singulair side effects: reactions of hypersensitivity, erythremia, nightmares, skin rash, hives, Quince's edema, hallucinations, drowsiness, fatigability, anxiety, hyperirritability, suicidal thoughts, insomnia, paresthesia. In very rare cases: seaizures, nausea, diarrhea, stomach pain, headache, arthralgia, myalgia, tendency to bleedings, increased heart rate, edemas.

How generic Singulair can interact with other medicines?

SINGULAIR may be administered together with other drugs, traditionally used for prevention and long-term treatment of bronchial asthma. The recommended clinical dose of montelukast did not caused clinically significant effect on the pharmacokinetics of the following drugs: theophylline, prednisone, prednisolone, oral contraceptives (ethinyl estradiol / norethindrone), terfenadine, digoxin and warfarin.

AUC was decreased in patients while receiving phenobarbital (approximately 40%), but the correction of dosing regimen of generic SINGULAIR in such patients is not required.

Treatment with bronchodilators: SINGULAIR can be taken in patients which do not react to other  medicines used for bronchial asthma. Generic Singulair enhances the effect of inhaled corticosteroids and can be used in combination with them. The application of Singulair with inhaled corticosteroids allows reducing the dose of corticosteroids.

Singulair should not be taken when you receive the therapy with certain seizures medications. These drugs may decrease the blood levels of montelukast in the blood making the medicines ineffective. The list of anticonvulsants includes carbamazepine, primidine, Phenobarbital, phenytoin, fosphenytoin, pentobarbital and others.

Generic Singulair - Frequently asked questions

What is generic Singulair?

Generic Singulair is not a brand preparation. Generic means that the medication contains the same active ingredient as brand preparations. Generic drug possesses the same therapeutic effect as brand preparation. However, the excipients, color and form of tablets are different

Do I need a prescription to buy generic Singulair online?

Yes. After placing an order you need to send us a prescription. If you do not have a prescription please consult our customers support service.

Who is the manufacturer of generic Singulair?

Generic Singulair which we provide is made by Cipla - well known drug manufacturers. All of the drugs made by Cipla correspond to GMP standards of quality.

This info corresponds to official PIL provided by legal manufacturer and reviewed by: Dr. Rohit Bansali N.

No customer reviews for the moment.

Add Review
hide form
  Add review

No customer questions for the moment.

Ask a question
Your Question has been successfully sent our team. Thanks for question!
Ask a question
hide form
  Ask a question

Customers who bought this product also bought: