Elidel cream is a dermotropic...
Elidel cream is a dermotropic anti-inflammatory drug, a selective inhibitor of the synthesis and release of inflammatory mediators. Elidel (pimecrolimus) effectively reduces skin inflammation and pruritus in patients with atopic dermatitis.
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Elidel cream is a dermotropic anti-inflammatory drug, a selective inhibitor of the synthesis and release of inflammatory mediators. Elidel (pimecrolimus) effectively reduces skin inflammation and pruritus in patients with atopic dermatitis. It is indicated to treat mild to moderate atopic dermatitis (atopic eczema) in adults and children.
Elidel cream is a potent anti-inflammatory medication. After local application Elidel cream
effectively reduces skin inflammation and pruritus, normalises histopathological changes in hairless rats with hypomagnesemia, which are models of atopic dermatitis of acute phase. Compared with tacrolimus, Elidel (pimecrolimus) easily penetrates skin structure and cells where exerts its therapeutic effect.
Elidel (pimecrolimus) is effective for skin inflammation, while its effect on the systemic immune response is very low. In general, a unique mechanism of action of Elidel is in the combination of anti-inflammatory activity and selectivity for the skin, with a low potential to cause systemic immune responses.
Elidel cream is used for mild to moderate atopic dermatitis (atopic eczema) in patients:
Elidel is indicated for short-term and intermittent long-term use in adults and in adolescents.
Mode of administration
A thin layer of Elidel 1% cream is applied two times a day, gently rubbing until it is completely absorbed.
Elidel 1% cream can be applied to the skin of any body parts, including head, face, neck, and in the field of diaper rash.
Elidel cream should be applied 2 times a day until symptoms disappear.
Elidel treatment should begin with the first manifestations of the disease to prevent the development of complications. At intervals in the treatment of the use of Elidel should be resumed immediately at the first symptoms of relapse.
Emollients can be applied immediately after Elidel 1% cream applications.
Since the degree of systemic absorption of Elidel is extremely small, there is no limit on daily dose.
If symptoms persist for six weeks of treatment with Elidel make sure to let your doctor know.
You should not use Elidel cream under occlusive dressing.
Contraindications and cautions
Elidel cream 1% is contraindicated for with known hypersensitivity to any of the drug ingredients
Elidel during pregnancy and lactation:
The application of Elidel 1% cream during pregnancy is possible only when benefits for mothers overweights potential risk for the baby. There is no adequate data on the use of Elidel cream 1% in pregnant women. Studies in animals with topical application of Elidel did not indicate direct or indirect effect on pregnancy, the developing embryo/fetus during labor.
Lactating women should stop breast-feeding during the treatment with Elidel.
Elidel side effects
Elidel may cause the following side effects:
The use of Elidel 1% cream may cause minor transient reactions at the site of application, such as a feeling of warmth and burning.
The most commonly reported side effects were application site reactions which occurred in 19% of patients treated with Elidel cream 1%, and 16% of patients in the control group. These reactions generally occurred early in treatment, were mild/moderate and transit.
Most common Elidel side effects included:
Elidel special cautions
Precautions and special instructions:
Elidel cream should not be applied to the skin affected by acute viral infection. In case of skin infections of bacterial or fungal nature an appropriate antimicrobial therapy should be carried. If this infection symptoms persist, Elidel cream should not be used as long as the infection is completely cured.
Patients with atopic dermatitis are predisposed to skin infections, and initial treatment Elidel may increase the risk of infection by viruses varicella zoster (chickenpox or shingles) and herpes simplex, eczema herpeticum.
Local reactions (burning sensation at the site of application), which appear in the first few days of Elidel cream application (usually disappear within no more than 5 days), have mild or moderate severity and pass away with improvements.