The information provided below corresponds to the official product information from Patient Information Leaflet provided by the manufacturer.
The text does not contain any of medical advices, mode of administration and prescription plans.
Before beginning any treatment, we kindly advise you to consult your healthcare provider.
Ciprofloxacin antibiotic. Ciprofloxacin 500mg
Ciprofloxacin is a bactericidal antibiotic which is also known as Generic Cipro. It is used for treating the infections from the respiratory system, abdominal infections, sexually infections, genital infections and gastrointestinal infections. Ciprofloxacin is an antibiotic from the fluoroquinolone group. The medication comes in the form of Ciprofloxacin 500mg tablets.
Ciprofloxacin is stopping the production of bacterial proteins by inhibiting the DNA-gyrase which is controlling the synthesis of the bacterial proteins. This way, the infections are stopped and the bacteria are eliminated from the human body.
The spectrum of antibacterial activity includes gram-positive and gram-positive microorganisms: Listeria, Corynebacterium, Escherichia Coli & Shigella, Acinetobacter, Brucella, Streptococcus agalactiae, Chlamydia, Branhamella, Staphylococcus, Pasteurella, Haemophilus, Enterobacter, Serratia, Hafnia, Salmonella, Citrobacter, Klebsiella, Edwardsiella, Proteus (indole-positive and indole-negative), Providencia, Morganella, Neisseria, Moraxella, Yersinia, Vibrio, Aeromonas, lesiomonas, Campylobacter, Pseudomonas, Legionella.
Ciprofloxacin antibiotic is effective against bacteria which produce beta-lactamases. The sensitivity to ciprofloxacin varies in: Mycoplasma hominis, Mycobacterium tuberculosis, Mycobacterium fortuitum, Streptococcus viridans, Gardnerella, Flavobacterium, Streptococcus pyogenes, Streptococcus pneumonia, Alcaligenes, Streptococcus faecali.
The following microorganisms are resistant to generic Cipro: Nocardia ahormones, Streptococcus faecium, Ureaplasma urealyticum, Anaerobic microorganisms are moderately sensitive to Ciprofloxacin (Peptococcus,Peptostreptococcus) or resistant (Bacteroides). Ciprofloxacin does not act on Treponema pallidum and fungi. The resistance to Cipro generic is developed gradually and slowly.
Ciprofloxacin antibiotic is active against pathogens which are resistant to beta-lactam antibiotics, aminoglycosides and tetracyclines. The medication does not change intestinal and vaginal microflora.
Ciprofloxacin antibiotic is successfully used to treat systemic infections (with the exception CNS infections) which are caused by sensitive to the medication ingredients: infections of the respiratory system, ENT infections, gynecological infections, sexually transmitted infections including gonorrhea, infections of the abdominal cavity and gastrointestinal tract. Ciprofloxacin is the most used antibacterial remedy in clinical practice.
Mode of administration and recommendations of usage:
Ciprofloxacin 500mg is the most common dosage offered by the doctors, because Ciprofloxacin is a very powerful antibiotic, that’s why the kids under 18 years mustn’t start a treatment with Ciprofloxacin. For severe medical problems, Ciprofloxacin should be taken three times per day, for a period of time fixed by a specialist. This antibiotic is also used for eye infection too.
Ciprofloxacin should be taken only under medical control, because it can bring an overdose if taken without a normal treatment and dosage. As any other types of antibiotic, Ciprofloxacin can be taken with a glass of water only. Because it’s very powerful, it never should be taken without food in the stomach, because it can bring nausea symptoms. This tablet shouldn’t be chewed because it won’t have any effect.
Contradictions and cautions:
Ciprofloxacin antibiotic shouldn’t be taken if a patient is already following a treatment with vitamins or herbs, because both of them can affect the whole body. Also, the Ciprofloxacin is raising the level of creatinine from the human body. Also, the inflammatory drugs in combination with Ciprofloxacin can severely affect the Central Nervous System, and that’s how the side effects are appearing.
Do not use Ciproflocain antibiotic in:
- Pseudomembranous colitis
- Children (under 18 years of age)
- Hypersensitivity to ciprofloxacin and other quinolone antibiotics
- Low potassium blood levels
- Epilepsy or seizures
- Pregnancy (Ciprofloxacin is a pregnancy category C meaning that is unsafe to the drug during pregnancy)
- Breastfeeding (Cipro can pass through breast milk). Therefore the medication should be avoided in breastfeeding mothers
Ciprofloxacin should be used with caution in:
- Atherosclerosis of the cerebral blood vessels
- Disorders of the brain circulation
- Psychotic diseases
- Liver failure
- Prolonged QT interval
- Reactions of hypersensitivity
- Renal insufficiency (renal failure)
- Elderly age
Ciprofloxacin and breastfeeding should be avoided, because both of them can affect even the mother and also the milk offered to the baby. Also, Ciprofloxacin antibiotic in pregnancy it’s not recommended, because the patient might have difficulties with the pregnancy and even worse, she can lose the baby.
The side effects produced by the Ciprofloxacin 500mg or Generic Cipro are very different from other antibiotics. They can change the smell and taste senses and the vision. Also, fever, skin itching cardiovascular problems, digestive problems such as nausea, vomiting, diarrhea or abdominal pain might appear during the Ciprofloxacin treatment.
You should inform your doctor if you take prescription and non-prescription drugs, minerals, vitamins, herbal supplements.
•Simultaneous use of theophylline and Ciprofloxacin results in increase of its concentration in blood plasma, so it is necessary to adjust theophylline dosing regimen.
Cipro enhances nephrotoxicity in cyclosporine, leading to increased levels of creatinine.
•Simultaneous use of non hormonal anti-inflammatory drugs (NSAID's) and generic Cipro may increase the risk of Cipro side effects on central nervous system.
Concomitant application with probenicid (or other drugs that block tubular secretion) leads to a decrease in renal excretion of ciprofloxacin.
- Metoclopramide accelerates the absorption of ciprofloxacin
- Ciprofloxacin antibiotic increases a half life periods of xantines and hypoglyecemic drugs
- In concomitant application with antacids containing magnesium hydroxide or aluminum hydroxide the absorption of ciprofloxacin is reduced.
- Ciprofloxacin antibiotic enhances the effects of oral blood thinners (anticoagulants such as Warfarin)
- The drug enhances the effects of glyburide and may cause significantly low blood sugar levels
- Ciprofloxacin 500mg may enhance the effects of other antibiotics (beta-lactam, aminoglycosides, cephalosporins).
- The medication may also interacts with: tizanidine (Zanaflex®), tricyclic antidepressants, phenytoin, antiarrhythmics, antipsychotic medicine, diuretics, hormones, cortical hormones, methotrexate, sucralfate, didanosine
This info corresponds to official PIL provided by legal manufacturer and reviewed by: Dr. Rohit Bansali N.