ACC 200mg is used for respiratory...
ACC 200mg is used for respiratory diseases, accompanied by the formation of a viscous sputum (acute and chronic bronchitis, obstructive bronchitis, pneumonia, bronchiectasis, bronchial asthma, bronchiolitis, cystic fibrosis);
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Dosage form, composition and packaging
Effervescent tablets, white, round, flat, with the smell of blackberry
Mucolytic drug. The presence of sulfhydryl groups in the molecular structure of acetylcysteine helps to break the disulfide bonds of acid mucopolysaccharides of mucus, which leads to reduction in mucus viscosity. It has mucolytic action, facilitates expectoration due to the direct impact on the rheological properties of sputum. The drug remains active in the presence of purulent sputum.
In case of prophylactic use of acetylcysteine there is a marked decrease in the frequency and severity of exacerbations in patients with chronic bronchitis and cystic fibrosis.
ACC 200 Overdose
In case of accidental or intentional overdose such symptoms as diarrhea, vomiting, stomach pain, heartburn, nausea are observed. So far, no severe and life-threatening side effects have been observed.
ACC 200 interactions
In case of simultaneous use of acetylcysteine and antitussives due to suppression of the cough reflex the dangerous stagnant mucus may occur (combination should be used with caution).
In case of simultaneous use of acetylcysteine and nitroglycerin vasodilator effects of nitroglycerin may be increased.
The synergism of acetylcysteine with bronchodilators has been noted.
Acetylcysteine reduces the absorption of cephalosporins, penicillins and tetracyclines, so they should be taken orally no earlier than 2 hours after taking acetylcysteine.
Acetylcysteine is pharmaceutically incompatible with antibiotics (penicillins, cephalosporins, erythromycin, tetracycline and amphotericin B) and proteolytic enzymes.
After contact of acetylcysteine with metals and rubber sulfides with a characteristic odor are formed.
ACC 200 in Pregnancy and lactation
Because of insufficient data the use of drug during pregnancy and lactation is possible only in those cases where the intended benefits to the mother outweigh the potential risk to the fetus or child.
ACC 200 Side effects
Nervous system: rare - headache, tinnitus.
Digestive system: rare - stomatitis; very rare - diarrhea, vomiting, heartburn and nausea.
Cardiovascular system: very rarely - decreased blood pressure, tachycardia.
Allergic reactions: in isolated cases - bronchospasm (predominantly in patients with bronchial hyperreactivity), skin rash, itching and urticaria.
Miscellaneous: in isolated cases - bleeding as a manifestation of hypersensitivity reactions.
Storage time and conditions
The drug should be stored out of children’s reach in a dry place at a temperature not exceeding 25°C. Shelf life - 3 years.
After taking a tablet the tube should be closed tightly.
ACC 200 Indications
ACC 200 Contraindications
The drug should be used with caution in patients with esophageal varices, with an increased risk of pulmonary hemorrhage and hemoptysis, in case of bronchial asthma, diseases of the adrenal glands, liver and/or kidney failure.
ACC 200 Cautions
In case of bronchial asthma and obstructive bronchitis acetylcysteine should be used with caution under the systematic control of bronchial patency.
In case of development of adverse reactions the patient should stop taking the drug and consult a doctor.
Glassware must be used for dissolving the drug, avoid contact with metals, rubber, oxygen, easily oxidized materials.
When treating patients with diabetes one needs to take into account that 1 effervescent tablet of ACC 100 and ACC 200 corresponds to 0.006 BU.
Effects on the ability to drive and use machines
There is no information about the negative effects of the drug in recommended doses on the ability to drive and perform other activities that require concentration and rapid psychomotor reactions.
In case of renal impairment
The drug should be used with caution in patients with renal insufficiency.
In case of abnormal liver function
The drug should be used with caution in case of hepatic failure.
ACC 200 Application in children
Contraindications: children under 6 years of age (the drug in the form of granules for oral solution 200 mg); children under 14 years of age (dosage forms of the drug with the content of acetylcysteine 600 mg).